Collaborative CCCR Speaker Series Presentation: Nikki Freeman, PhD
Event Details
The next presentation of the Collaborative Core Center for Clinical Research (CCCR) Speaker Series is on Wednesday, September 27th from 9:30-10:30am ET (8:30-9:30:00am CT and 6:30-7:30am PT)!
This event will be held virtually, register to attend here!
Individualized Treatment Rule Characterization Via Surrogate for the Value Function
Nikki Freeman, PhD
Postdoctoral Research Associate Vascular Division
Department of Surgery UNC School of Medicine University of North Carolina at Chapel Hill
Abstract: Precision medicine is a promising framework for generating evidence to improve health and health care. Yet, a gap persists between the ever-growing number of statistical precision medicine strategies for evidence generation and implementation in real world clinical settings, and the strategies for closing this gap will likely be context dependent. In this talk we will provide a friendly introduction to statistical precision medicine and what to this point have been common precision medicine tasks, evaluating treatment rules and learning optimal treatment rules. We will then consider the specific context of partial compliance to wound management among patients with peripheral artery disease. We will show how the use of a Gaussian process surrogate for the value function can help us expand beyond the common precision medicine tasks to characterization of classes of individualized treatment rules and how those findings aid translation of precision medicine evidence into clinical contexts.